If you’re spending quite a lot of time on the computer, chances are, you’ve had at least some experience with wrist pain. In order to eliminate the wrist issues and keep on working without any impediment, you should consider purchasing a vertical mouse.

In order to find the best vertical mouse for your needs, you’ll need to pay attention to several factors.

Firstly, the vertical mouse is designed to keep your hand in its natural position, so its admittedly awkward design is an excellent benefit in the long run. Size is also important because you want the mouse that fits your hand like a glove. Smaller or bigger mice can get pretty uncomfortable after a time.

Secondly, watch out for the DPI. If you’re a graphics designer, DPI is the key: the higher the DPI, the higher the precision level, but you don’t need to be a designer to enjoy the benefits of high-level precision.

Thirdly, multiple programmable buttons on your mouse are a blessing, since they increase your work efficiency on a pretty noticeable level. Their presence or absence doesn’t need to be the deciding factor, but they’re still neat to have for any kind of professional work.

Top Picks:

7 Best Vertical Mice

Logitech MX Vertical Wireless Mouse

Wireless Professional

logitech mx vertical wireless mouse
Logitech has always been a golden standard when it comes to high-quality ergonomic mouse, and their vertical mouse series does not disappoint.

MX Vertical Wireless Mouse boasts with an ergonomic design, which is a real blessing for all people who use mice for extended periods of time. Due to its verticality and the 57-degree angle, your hand will be naturally placed in the handshake position. This design reduces the strain in your muscles by up to 10%.

When it comes to precision, MX shines with amazing 4000 DPI! This means that you’ll need less hand movement than your traditional 1000 DPI mouse. This sort of precision and reduced movement comes with another benefit: further reduced muscle strain.

Thanks to Logitech Flow technology, MX vertical mouse can be connected to up to three computers, allowing it to copy text and images. The computers can be either Windows or Mac-powered, but not mixed.

Connectivity is another amazing feature of this mouse. Not only it can work on three computers simultaneously, it supports both standard wireless and Bluetooth connection technologies, with up to 10 meters of connection range.

Finally, Logitech MX has impressive battery life. You can work without any issues for up to 4 months, depending on the intensity of working conditions. Overall, Logitech MX offers quite a lot under the hood, and it’s maybe the best ergonomic vertical mouse on the list.

Pros:
  • Ergonomic design
  • High precision
  • Battery life
Cons:
  • Pricier than your average mouse

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Evoluent VM4R Vertical Mouse

Fit In Specialist

evoluent vm4r verticalmouse
Evoluent’s VM4R is quite a beast of a vertical mouse, more than capable to satisfy both your professional and your gaming needs.

Like the previous entry on our list, VM4R is ergonomically designed to reduce muscle strain and eliminate discomfort during use. Since you don’t need to twist your wrist like when using the normal mouse, your hand will always be in the natural, neutral position, so the risk of strain is all but eliminated.

VM4R boasts with great programmability. The extra buttons on the mouse can be programmable to suit your needs. You can not only assign them specific commands but can also control what they do in different programs and games!

Even the pointer speed is adjustable! The side controls on this mouse can be used to control the pointer speed, so you can easily set from high to low.

VM4R boasts with great connectivity, being easy to use on both Windows and Mac computers, but unlike the previous entry on our list, it can be used on a Linux-powered computer too, though only in basic mode.

Whether you’re looking for a mouse for work or gaming, do pay attention to VM4R. It definitely falls into the best vertical mouse category!

Pros:
  • Ergonomic design
  • Great connectivity
  • Pointer speed adjustment
  • Standard USB wireless and wired connection
Cons:
  • High price

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Anker 2.4G Wireless Vertical Ergonomic Optical Mouse

Champion of Comfort

anker 2 4g wireless vertical ergonomic optical mouse
Anker’s vertical mouse is one of the most affordable items on our list, but its low price does not mean low quality!

This vertical mouse’s ergonomic design allows for the natural handshake position of your wrist, so the strain in the muscles of your hand an arm is no longer a cause for concern. It’s slick and smooth, and due to its size, it’s no wonder it fits the best vertical mouse for small hands category so well!

As for precision, Anker Vertical Mouse boasts with adjustable pointer precision.

Much like the previously listed mouse, you can program the precision in three modes, with 800 DPI, 1200 DPI (the default setting), and 1600 DPI respectively. This allows for precise and reliable work on many different surfaces.

The side buttons make this mouse easy to use, which is a feature both professional users and gamers can find as a great benefit, but you can also use them to casually scroll through web content as well. It can be used on Windows, Mac, and Linux systems.

Pros:
  • Ergonomic design
  • Adjustable pointer precision
  • Very affordable price;
  • Power saving mode
Cons:
  • Side buttons issues on Linux

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Adesso iMouse E10

Buttons That Control It All

adesso imouse e10
Adeso’s iMouse E10 is quite a little gem when it comes to vertical mice. Not only does its design allow for more relaxed and natural hand and arm posture, but it also provides the equally high maneuverability and ease of use no matter the size of the user’s hands.

iMouse E10 boasts with the powerful 2.4 GHz connection with the range of up to 30 ft in any angle, and since this is a wireless mouse, you won’t need to worry about cables getting entangled all across your workspace. This mouse is one of the best wireless vertical mice on the list.

This mouse also comes with a button for pointer precision adjustment, which makes the switch between 800, 1200, and 1600 DPI fluid and seamless. There are also forward/backward buttons on the side, which always come in handy for all surfing, working and gaming situations.

The ease of use is further underlined by iMouse’s Plug’n’Play feature: just plug the mouse in and it’s ready to go; no additional drivers needed!

Pros:
  • Ergonomic design
  • Connectivity
  • Price
Cons:
  • Not supported on Linux systems

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LEKVEY Vertical Wireless Mouse

The Undying – Forget The Batteries

lekvey vertical wireless mouse
Lekvey’s wireless vertical shares the low price of Anker’s mouse and it has quite a lot to offer as well!

Slick and smooth ergonomic design goes without saying, and it’s easy to use no matter the size of your hands. The verticality allows for a natural hand and arm posture, which consequently provides the comfort and precision needed for working for prolonged periods of time.

This mouse comes equipped with forward/backward side buttons, perfect for casual gaming, page scrolling, and also for moving and marking large amounts of data, and of course, there is a button for pointer precision adjustment to 800, 1200, and 1600 DPI.

This wireless mouse can be used on Windows and Linux systems and has solid battery life. The battery itself is easily rechargeable via charging cable.

Pros:
  • Affordable price
  • Ergonomic design
  • Built-in battery
Cons:
  • This model does not support Mac OS

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Jelly Comb Wireless Vertical Mouse

Cute and Comfy

jelly comb wireless vertical mouse
Jelly Comb’s wireless vertical mouse comes with super sweet features and is the most cost-friendly mouse on this list.

Just like all the other mice on this list, Jelly Comb’s mouse is designed to keep the hand in the natural handshake position in order to reduce the wrist and muscle strain, allowing for prolonged periods of use. Due to its size, it’s the best vertical mouse for small hands on this list.

It comes equipped with both the standard and the side buttons for forward/backward navigation, perfect for effortless browsing and gaming, and there is also a button for pointer precision adjustment. With a simple click, you’ll be able to jump from 800 to 1200 to 1600 DPI.

When it comes to clicks, this mouse boasts with admirably low levels of noise during work, so you won’t be able to worry about the clicking sound, and most notably, the main buttons have passed the 5 000 000 clicks test.

Pros:
  • Ergonomic design
  • Stable connection
  • Quiet working hours
Cons:
  • AA battery not included in the package
  • Not properly supported by some MacOS systems

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J-Tech Digital Wired Ergonomic Vertical USB Mouse

Gaming Master

j-tech digital wired ergonomic vertical mouse
The final entry on our list and another of the more cost-friendly vertical mice, J-Tech Digital Wired Ergonomic Vertical Mouse is a rather beautiful and efficient large-handed mouse model.

The ergonomic design is as per the standard, so the wrist strain is all but eliminated, and with blue LED lights around it, J-Tech’s mouse looks like a real cyberpunk model, which will definitely appeal to many gamers.

Unlike other models on our list, this mouse goes with a removable palm rest, which you can attach and remove whenever you wish, and thus reduce the drag on your work surface.

Just like other vertical mice we listed, this model also has all the usual side buttons and the DPI switch, supporting 800, 1200, and 1600 DPI settings.

The forward/backward thumb buttons can also be programmable for other functions, which makes it possibly the best vertical mouse for gaming on the list.

This wired mouse boasts with great flexibility in terms of use, and it’s supported by Windows, Linux, and Mac OS operating systems. A great bonus feature is the free lifetime support – J-Tech has you covered in case of any issue you may find during use.

Pros:
  • Ergonomic design
  • Maximum comfort
  • Cost-friendly
  • Programmable buttons
Cons:
  • None so far

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Conclusion

We have tried to provide you with the list of some of the best vertical mouse models on the market. Be it work, graphics design, or gaming, these models will suit all of your needs, and the best part is: you won’t need to worry about your hand and wrists again!